Focus Stack — Starter Protocol
A simple, evidence‑guided stack to boost mental clarity and steady focus during the workday. Start low, track response, and adjust one change at a time.
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Morning quick-start
⭐ AM plan boosts alertness, attention stability, and mental stamina.
Omega‑3s (EPA/DHA) 1–2 g with breakfast — supports faster signaling and attention stability.
Creatine 3–5 g with breakfast — mental stamina via neuronal ATP.
Pick ONE cholinergic
- Citicoline (CDP‑Choline) 250–500 mg AM — default daily option for baseline, jitter‑prone, or sleep‑sensitive
- Alpha‑GPC 300–600 mg AM only — optional punchier alternative for time‑boxed deep‑work or presentation days
Caffeine 100–200 mg after breakfast — smoother absorption and fewer jitters, stabilizes energy curve, reduces gut stress
Optional: CoQ10 100–200 mg with fat‑containing breakfast — steadier afternoon energy.
Evening wind‑down
⭐ Stronger sleep tonight → better focus and mental clarity tomorrow.
Dim screens and lower lights 60–90 min before bed
Wind‑down routine started on time
Magnesium (glycinate or L‑threonate) 100–200 mg elemental, 60–90 min pre‑bed.
Caffeine cutoff respected 8–10 hours before bedtime
Why this works (in brief)
Statements on this site have not been evaluated by the Food and Drug Administration.
Products and information are not intended to diagnose, treat, cure, or prevent any disease. Learn More
Products and information are not intended to diagnose, treat, cure, or prevent any disease. Learn More
Mechanism | What it does | Why it matters for focus |
Alerting + dopamine tone | Caffeine supports vigilance and task initiation | Raises subjective energy and helps you get started on demanding work |
Membrane and signaling → attention stability | Omega‑3s (EPA/DHA) enrich neuronal membranes and support vascular function | Improves synaptic efficiency for clearer thinking and steadier attention |
Acetylcholine pathway | Citicoline or Alpha‑GPC provide choline to support acetylcholine transmission | Enhances working memory, cue detection, and sustained attention |
Cellular energy → focus stamina | Reduces mental fatigue and helps maintain performance in long work blocks | |
Sleep‑to‑focus link | Magnesium can improve sleep quality | Better sleep architecture supports next‑day attention and clarity |
Week‑by‑week ramp
Week 2
Layer ONE cholinergic (citicoline OR alpha‑GPC). Keep dose modest.
Layer ONE cholinergic (citicoline OR alpha‑GPC). Keep dose modest.
Week 4
If evenings are wired, address sleep hygiene; consider magnesium.
If evenings are wired, address sleep hygiene; consider magnesium.
TIP: Change only one variable per week when possible. Keep a 1–10 focus score daily.
Dosing cheat sheet
Supplement | Dose | Timing | Notes |
100–200 mg per dose, cap ~400 mg/day | AM, avoid within 8–10 h of bedtime | May raise anxiety or BP; smaller PM top‑ups only if sleep unaffected | |
1–2 g/day EPA+DHA | With breakfast | Supports signaling and attention stability | |
500–1,000 mg/day total | AM | Default daily cholinergic; gentler feel, sleep‑friendly | |
300–600 mg/day | AM only | Alt for punchier effect; avoid late dosing | |
3–5 g/day | Any time with a meal | Mental stamina via neuronal ATP; prioritize daily consistency | |
100–200 mg/day | With fat‑containing meal | May steady afternoon energy dips | |
100–400 mg elemental | Evening, 60–90 min before bed | Start low; separate from certain meds by 2+ hours |
Safety and interactions (scan before you start)
- Caffeine: May worsen anxiety, elevate HR/BP, and aggravate reflux. Interacts with stimulants, certain antibiotics, clozapine, lithium. Pregnancy: often limit to ~200 mg/day.
- Omega‑3s: Bleeding risk with anticoagulants/high‑dose NSAIDs; mild BP and triglyceride effects. Allergy caution with fish products; algal DHA/EPA is an option.
- Citicoline / Alpha‑GPC: Headache or insomnia in some; use caution with other cholinergic agents; avoid late dosing.
- Creatine: Generally well tolerated; caution with kidney disease, dehydration, or nephrotoxic drugs.
- CoQ10: May affect warfarin dosing; monitor INR.
- Magnesium: Separate by 2+ hours from some antibiotics and thyroid meds; GI looseness signals dose/form issues.
AM/PM routine
Tracking
Sunday’s date: _______________
ㅤ | Focus 1–10 | Energy 1–10 | Jitters 0–3 | Sleep 1–10 | Notes |
Sunday | |||||
Monday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Tuesday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Wednesday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Thursday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Friday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Saturday | ㅤ | ㅤ | ㅤ | ㅤ | ㅤ |
Weekly reflection
- What changed?
- Keep or adjust?
- Any side effects?
Explore top supplement candidates for Focus & Mental Clarity
Brain-Gut Supplements
Starter Stacks — AM/PM notes for quick use of Top Picks.
Tip: Open any candidate to see mechanisms, dose ranges, interactions, and stack notes. Add to your personal plan if helpful.
